What drug(s) may interact with sildenafil?
Start
Do not take sildenafil if you are taking the following medications:
•nitroglycerin-type drugs for the heart or chest pain such as amyl nitrite, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin, even if these are only taken occasionally
Sildenafil may also interact with the following medications:
•alpha blockers, used for high blood pressure or an enlarged prostate. NOTE: Do not take doses of sildenafil higher than 25 mg within 4 hours of taking alpha blockers, such as alfuzosin (UroXatral®), doxazosin (Cardura®), prazosin (Minipress®), or terazosin (Hytrin®).
•bosentan
•certain drugs used for seizures such as carbamazepine, phenytoin, and phenobarbital
•certain drugs used for fungal or yeast infections, such as fluconazole, ketoconazole, and voriconazole
•certain drugs for the treatment of HIV infection or AIDS
•cimetidine
•cisapride
•clarithromycin
•diltiazem
•erythromycin
•grapefruit juice
•mibefradil
•monoamine oxidase inhibitors (Azilect®, Eldepryl®, Emsam®, Marplan®, Nardil®, Parnate®, Zelapar™)
•nitroprusside
•rifabutin
•rifampin
•quinidine
•some drugs for treating depression, anxiety or other mood problems (examples: fluoxetine, fluvoxamine, nefazodone)
•verapamil
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.